Prediction of mortality of APACHE-II and APACHE-III scores in patients admitted to the intensive care unit (ICU) for intoxication

Results We studied 119 patients. Mean age: 44.42 ± 13.85 years. Drug intoxication in 77.3% of patients, alcohol in 16.8% and caustic 9.2%. 78.3% was a suicide attempt. The mean Glasgow Coma Scale in 72.5% were < 8 points. 69.7% required mechanical ventilation. The mortality of patients hospitalized for caustic ingestion was 54.5% and 1.9% in the rest (p < 0.001). The multivariate analysis showed that with SAPS-3 equal gravity (OR: 1.19 (1.02-1.39)) the mortality of patients who ingested caustics was higher (OR: 560.34 (11.64-26.973.83)) than the rest. The mortality predicted by SAPS-3 (general equation) was 26.98% and the observed 6.7%, Hosmer-Lemeshow (H = 36.47) (p < 0.001). With the APACHE-II and APACHE-III scores no statistically significant differences were observed, being the predicted mortality for APACHE-II of 7.57% (Hosmer-Lemeshow Test: H = 6.96, no difference is) and for APACHE-III of 8.15% (HosmerLemeshow Test: C = 3.51, not discrepancies).